Promptly acquire sections as slim or thick as your software requires, without having stressing about getting rid of or distorting beneficial tissue samples.
Our switch-critical SmartBatch+ procedure brings together electrophoretic tissue clearing and immunolabeling into 1 substantial-throughput unit.
Antibodies may possibly acquire months to diffuse as a result of only some millimeters of tissue, with a steep labeling gradient from surface to Main.
Megatome is designed for accuracy: the blade vibrates at a higher frequency and larger amplitude range than other microtomes, and features a one of a kind deflection Command system.
SE works by using a rotational electric powered subject to disperse hugely electromobile molecules (including antibodies or surfactant micelles) all through a porous sample with out damaging electrically billed buildings within the tissue. This allows 2-four day clearing of intact organs,
Our preformulated EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them completely transparent. This enables light-weight penetration in the sample and assures the acquisition of higher-resolution, in-focus picture info.
Megatome is really a novel microtome which allows for top-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimum tissue destruction and data decline.
It’s time to update your microtome to Megatome. With exact high-frequency slicing for an unmatched selection of sample measurements and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.
The SmartSPIM light sheet microscope delivers unparalleled resolution and acquisition speed all over intact tissue volumes, although its modular design lets you upgrade and personalize individual parts.
Docset generation demands at least two choices: the title of the docset and The placement of the Javadoc information to incorporate while in the docset.
This will produce a docset named Sample in The existing directory. Docset development is usually personalized with optional arguments:
SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, guarding specimens for a number of rounds of processing.
--displayName: Will set the name as revealed in Sprint. This is helpful if you produce a docset with title SampleProject but Display screen identify Sample Job alternatively. This environment will default to the worth of --name if omitted.
Our megatomi.com novel Protect tissue preservation technique kinds intramolecular bonds working with polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.